Arthur Arnold Distinguished Lecture

Capstone Speaker

Janine Austin Clayton, M.D.
NIH Associate Director for Research
Director, ORWH

More about Dr. Clayton

Roberta Brinton, Ph.D.
Director, UA Center for Innovation in Brain Science
University of Arizona Health Sciences

More about Dr. Brinton


Special Symposium Highlights

The Role of the X Chromosome in Sex Differences in Health & Disease
Chairs:  Drs. Christine Disteche, University of Washington, Rhonda Voskuhl, UCLA

On the “Nature” of sex and gender research. Dr. Cara Tannenbaum, CIHR, CRIUGM

X chromosome mechanisms shown in immune responses relevant to health and disease.  Dr. Rhonda Voskuhl, UCLA

X-inactivation escapee variation by cell and tissue type: The role in sex differences in health and disease.
 Dr. Christine Disteche, University of Washington

Sex Chromosome Dosage Effects on Gene Expression and Chromosome Organization in Humans.
 Dr. Armin Raznahan, NIMH

Differences of Sex Development: A window into sex and gender development 
Chairs: Drs. Natalie Nokoff, University of Colorado Anschutz Medical Campus and Eric Vilain, GW Children’s National Medical Center

Understanding Differences of Sex Development. Dr. Courtney Finlayson, Northwestern Feinberg School of Medicine, Lurie Children’s Hospital

Modern Genetic Approaches to DSD. Dr. Emmanuèle Délot, The George Washington University

Impact of sex steroids on neural stem cells. Dr. Eric Vilain, George Washington University, Children’s National Medical Center

Psychosocial outcomes in DSD and the impact of sex steroids on the brainDr. David Sandberg, University of Michigan

Multifactorial Determinants and Insights into Sex Differences in the Regulation of Energy Homeostasis 
Chair: Dr. Edward Wagner, Western University of Health Sciences

Sex Differences in, and dietary influences on, cannabinoid regulation of energy homeostasis. Dr. Edward J. Wagner, Western University of Health Sciences

Sex differences in progressive motor and metabolic phenotypes in the MeCP2-e1 deficient mouse model. Dr. Janine LaSalle, University of California, Davis

Sex differences in the drinking response to angiotensin II. Dr. Jessica Santollo, University of Kentucky

Estradiol Protects Proopiomelanocortin Neurons against Insulin Resistance. Dr. Oline Ronnekliev, Oregon Health and Science University



Neuroimmune Activity in Adolescence: Are sex differences all about puberty?
Chair: Dr. Heather Brenhouse, Northeastern University

Is perineuronal net formation during adolescence differentially regulated by microglial activity in males and females? Kelsea Gildawie, Northeastern University

Sex differences in blood brain barrier activity during adolescence. Dr. Gretchen Neigh, Virginia Commonwealth University

Sex-specific impact of immune signaling on dopaminergic signaling during adolescence. Dr. Ashley Kopec, Albany Medical College

Probiotic consumption during puberty mitigates LPS-induced immune responses and protects against stress-induced depression- and anxiety-like behaviors in adulthood in a sex-specific manner. Dr. Nafissa Ismail, University of Ottawa


Sex and Gender Differences in E-cigarette Use and Toxicity
Chairs: Drs. Meghan E. Rebuli, University of North Carolina, Chapel Hill and Patricia Silveyra, UNC Chapel Hill

Gender differences in perceived stress and e-cigarette use across adolescence.Dr. Jessica L. Barrington-Trimis, USC Keck School of Medicine

LGBT E-cigarette use and exposure to advertisements on traditional and social media. Dr. Kristen Emory, San Diego State University

Sex-Specific Effects of Nicotine Exposure: Differences between e-cigarette vapor inhalation and intravenous nicotine self-administration. Dr. Valeria Lallai, University of California, Irvine

Sex-dependent effects of E-cigarette in combination with other tobacco use on sleep quality. Dr. Laura Crotty Alexander, UC San Diego School of Medicine


Sex-Specific Therapies and Therapeutic Outcomes across Various Diseases
Chair: Dr. Katelyn Bruno, Mayo Clinic

Sex differences in cardio-oncology: utilizing a genetic variant as a therapeutic target for doxorubicin-induced cardiomyopathy. Dr. Katelyn Bruno, Mayo Clinic

Prohibitin: A potential target for sex-based new therapeutics for metabolic and immune diseases. Dr. Suresh Mishra, University of Manitoba

Combination of aromatase inhibitor exemestane and carboplatin-based therapy for postmenopausal women with advanced non-small cell lung cancer. Dr. Patricia Young, UCLA

Sex-specific studies in Parkinson's disease models for the repurposing of the gonadal drug Dutasteride. Dr. Amandine Isenbrandt, University of Laval